Short-term use of oral amiodarone causing torsades de pointes

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Torsade de pointes induced by short-term oral amiodarone therapy.

Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy. We report two cases of amiodarone-induced TdP shortly after administration of a low dose of oral amiodarone, in the absence of predisposing fact...

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Torsades de pointes following concurrent amiodarone and levofloxacin therapy.

A case of torsades de pointes is reported following administration of amiodarone concurrent with the fluoroquinolone levofloxacin. Prolongation of the QTc interval has occurred with the fluoroquinolone class of antibiotics. The incidence of torsades has been considered rare with amiodarone. Caution is warranted when these two agents are administered concurrently.

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L'intervalle de temps variable existante entre le debut du traitement par la prenylamine et la sur­venu de toisade de pointe et d'autre oart la raretee de· telle camplication est considere par les auteurs c0mme une indice de !'intervention de d'autres fac­teurs, parmie Jes quelles, la perturbation electroly­tique doit jouer le role principal. 

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Methadone-induced Torsades de pointes.

Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and sudden death. This arrhythmia often occurs secondary to medication- induced cardiac repolarization dysfunction with resultant prolonged QTc interval on ECG. Numerous medications can predispose patients to this deadly tachycardia. We report a case of methadone-induced Torsades d...

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Torsades de pointes: unanswered questions.

Torsade de pointes (Tdp) is a polymorphic ventricular tachycardia (VT) in which the axis of the QRS complex changes direction after a certain number of complexes as if the complex rotated around the baseline. Tdp is usually associated with QT prolongation, and dispersion of ventricular repolarlization (DR). Experimental models of tdp are usually associated with induction of early after depolari...

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2018

ISSN: 2050-0904

DOI: 10.1002/ccr3.1659